Frequently asked questions

Some of your most asked questions, answered

• Are there any ongoing research or studies about Nurosym?

  Yes, indeed! Nurosym is at the forefront of clinical research, continuously investing substantial resources into furthering our understanding and application of neuromodulation technology. With over $10 million deployed in clinical trials, we're dedicated to advancing the science behind our certified medical device.

  We collaborate with over 60 esteemed research organizations, including renowned institutions like Harvard and UCLU. Our commitment to transparency and excellence is underscored by our publication of over 30 papers in leading journals, such as Nature, showcasing our exciting and clinically significant results.

  It's important to note that all our studies are independently funded and led by investigators not affiliated with Nurosym. Most of our studies are randomized placebo-controlled trials, rigorously peer-reviewed, and published in high-quality scientific journals.

  For those interested in delving deeper into our research, we invite you to explore Clinical Evidence, where you can find comprehensive information on Nurosym studies. Healthcare professionals seeking additional insights into our studies, certification, or suggested treatment protocols can also reach out to us via email.

  Nurosym stands as the most studied neuromodulation system of its kind, widely regarded as the gold standard in clinical neuromodulation research.

   

  What are some of the benefits all of these studies have found?

  The following clinical benefits have been reporting in Nurosym clinical studies:

  • 61% increase in vagus Nerve Activity in 5 minutes
  • 90% increase in vagus nerve activity after 2 months of daily use
  • 18% increase in Heart Rate Variability
  • 13% improvement in sleep
  • 48% improvement in fatigue
  • 45% improvement in depression symptoms
  • 40% improvement in Long-Covid symptoms (fatigue, brain fog, pain, GI symptoms)
  • 40% improvement in POTS tachycardia
  • 78% improvement in inflammation
  • 28% reduction in oxidative stress
  • 32% improvement in memory
  • 29% improvement in reading
  • 50% improvement in macrocirculation
  • 39% improvement in microcirculation

   

  Disclaimer

  Clinical results are observed in specific study populations. Individual results may vary. Please note that the information provided here is for general informational purposes only and is not intended as medical advice. It’s important to consult with a qualified healthcare provider for diagnosis, treatment, and answers to your personal medical questions. If you do not have a doctor, reach out to our medical support, and we can help you find a solution.

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• How is Nurosym different from neck stimulation?

  While the first vagus nerve stimulators were indeed placed around the neck, they required risky and precise surgery to target the vagus nerve specifically. Stimulating the vagus nerve around the neck without precision poses significant risks, including self-afflicted stroke and severe cardiac complications. Stimulating the right side of the neck has been associated with risks of severe cardiac adverse events, such as bradycardia or cardiac arrest.

  For this reason, the FDA-approved labeling for vagal neuromodulation devices specifies that they should only stimulate the left vagus nerve in the neck area inside the carotid sheath, below where the superior and inferior cervical cardiac branches separate from the vagus nerve.

  Additionally, Mayo Clinic researchers have warned in the leading scientific journal, Scientific American, that tampering with the vagus nerve with unlicensed medical devices can potentially result in cardiac arrest or sudden death.

  On the other hand, Nurosym targets the vagus nerve via the ear (auricular branch). As the ear only contains sensory fibers of the vagus nerve, Nurosym’s proprietary Auricular Vagal Neuromodulation Therapy (AVNT) reaches the brain and activates the parasympathetic nervous system in the most natural and uniform way, overcoming the risks and limitations of neck stimulation.

  As a CE-Marked medical device, Nurosym has undergone 30+ clinical trials with 60+ ongoing studies involving thousands of participants to validate its safety. There have been 0 severe adverse events reported across all studies. Nurosym is recommended by doctors around the world as the most studied vagal neuromodulation system globally.

  Regulatory disclaimer

  Always verify device certification before purchase. CE Certification is the only valid medical device certificate in Europe. Beware of manufacturers using non-medical device certifications such as FCC certification. An FCC certification does not imply that the product is safe or durable. It simply means that it meets regulated limits for ionizing radiation. A certification does not imply that the device was manufactured in any specific way. FCC approval can be granted as long as the electronic device meets FCC emission rules and regulations and has been tested to comply with FCC standards. Exposing the nervous system to untested electrical current can risk permanent nerve damage, exacerbation of symptoms, or death.

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• Are there any side effects associated with Nurosym?

  As with any medical device, side effects are possible. However, we're happy to report that Nurosym is considered low risk when used as intended and boasts a very high safety profile. In fact, across all 30+ clinical studies conducted, there have been no reports of serious adverse events associated with Nurosym.

  While side effects are rare, it's important to be aware of potential experiences. The most commonly reported side effects include:

  • Tingling on the skin where the electrode is applied (paresthesia/dysesthesia)
  • Discomfort on the skin of the ear (Application site discomfort)
  • Application site irritation/redness - if this occurs, try applying a bit of moisture before use, shorten session times, or switch ears
  • In the initial weeks of use, a small proportion of patients may also experience temporary effects that typically subside within 1-2 weeks of continuous use due to adaptation. These effects may include nausea, headaches, confusion, malaise, or weakness.

  It's worth noting that in a published review of non-invasive neuromodulation clinical trials, only 2.6% of patients discontinued treatment due to side effects.

  Do you experience any distressing effects or transient effects beyond 2 weeks? We recommend discontinuing Nurosym use and contacting us via email for further assistance.

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• Can Nurosym be used alongside other treatments or medications?

  Nurosym can be a complementary tool alongside other treatments or medications for many individuals. However, there are specific contraindications to consider. These include:

  • Patients who have undergone surgery to cut the vagus nerve (cervical vagotomy)
  • Patients diagnosed with severe bradycardia
  • Patients with a permanent implanted metallic or electronic device or jewelry in close proximity to the ear tragus
  • Pregnant women

  Additionally, certain situations may be contraindications unless under the supervision of a medical doctor, such as patients with any active implanted device, severe coronary disease or recent myocardial infarction within 5 years, and pediatric patients.

  It's crucial to consult with your medical doctor to assess whether Nurosym is safe and appropriate for your specific circumstances, especially if you fall under any of these categories. Your doctor can provide guidance on potential precautions or supervision needed during Nurosym use. If you do not have a doctor you can contact, please reach out to our support and we’ll help connect you with the right person.

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• How do I get started using Nurosym?

  Getting started using your Nurosym is super easy.

  1. Apply a bit of moisture on the tragus (no gel needed)
  2. Wear the earpiece correctly on the tragus of your ear, the cable should go over and behind your ear to keep the electrodes in place.
  3. Press a button to turn on Nurosym
  4. Slowly increase energy level until you feel a light tingling sensation in your ear.
  5. Notice how pleasant the sensation of neuromodulation feels. This is a signal that the current is flowing and that your parasympathethic nervous system is activated.
  6. Perform normal daily activities while Nurosym works to strengthen your parasympathethic nervous system, decrease inflammation, oxidative stress and activate neuroplasticity to help you feel better.
  7. Notice the sensations of calmness, relaxation, decreased stress, improved mood, more energy flowing into your body.
  8. Continue using Nurosym every day for 30-60 minutes a day, preferably in the morning or split between morning after waking up and evening before sleep and enjoy better health & mood.

   

  You can also watch a video of Dr. Denef explaining how to use Nurosym here.

   

  Nurosym is versatile and convenient, allowing you to wear it during various activities such as reading, working, cooking, meditating, watching TV, or socializing. Simply press the button to activate. Using Nurosym during meditation enhances neuroplasticity, while during breathing sessions, it promotes relaxation and improves HRV. Before bed, it aids in better sleep, and in the morning, it releases tension and boosts energy. While working or studying, it enhances focus and learning and reduces tension. Additionally, you can use Nurosym as needed during or after stressful events or workouts to recover faster, during meals for digestion, or for pain relief.

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• How do I find the right energy level?

  Gradually increase the energy level until you feel a light tingling sensation, as this varies among individuals and may change day by day. Adjust the level during the session: increase if the sensation fades and decrease if it becomes too intense. The right level is when you feel the tingling without pain or discomfort in your tragus. If irritation occurs, shorten the stimulation time rather than lowering the energy level to ensure therapeutic effectiveness. As long as you feel the sensation without pain, you're using Nurosym correctly.

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• Can I use Nurosym while sleeping or exercising?

  We do not recommend using Nurosym while sleeping or exercising due to safety considerations. It's important to use Nurosym in a controlled environment where you can remain aware of its effects. Always prioritize your safety and well-being when using Nurosym.

  Nurosym is designed to be versatile and convenient, allowing you to wear it during various activities such as reading, working, cooking, meditating, watching TV, or socializing. We recommend incorporating Nurosym into your daily routine, aiming for 60 minutes per day to experience its beneficial effects, which can be felt in as little as 5 minutes. Using Nurosym before bed can help improve sleep quality. Additionally, you can use Nurosym as needed during or after stressful events or workouts to aid in faster recovery, during meals to assist with digestion, or for pain relief. 

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• Can I share my Nurosym with others?

  All Parasym clinical research has been conducted with each participant using their own personal device. To ensure the safest and most effective experience, we recommend that every individual user has their own device. Patient registration is done for each personal device to guarantee safe use.

  If you do choose to share a device, we strongly advise using separate biocompatible components (such as earpieces) and ensuring that the other user is safe to use the technology.

  Looking to purchase an extra earpiece? You can do so by clicking here.

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• Do I have to use a conductivity gel?

  No gel is required. A small amount of moisture, such as a drip of water, works well on the tragus. Conductive gel is also an option.

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• How do I know if Nurosym is working for me?

  You'll know Nurosym is working for you if you can feel the sensation of neuromodulation without any pain. In terms of seeing results, initial results might be noticeable from as little as 5 days of use. However, it's important to use Nurosym consistently for relief and recovery from chronic autonomic dysregulation symptoms, which may take 4 to 12 weeks.

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